Best bibliography management systems?

A question for readers who happen to manage bibliographies: what, if any, bibliography management systems do you use?

I started using Aigaion for mine. Then I found out that there’s an open system called bibsonomy, which is potentially much better since it lets you tag and share bibliographies socially, and it seems to already know about all the major computer science papers.

Again (see: The problem with standards), I’m frustrated by the fact that I can’t move my data around between applications as I like without lots of manual effort. A worthy research problem would be making data truly application independent once and for all.

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